What is PABA?

Para-aminobenzoic acid, commonly known as PABA, is a nutrient that belongs to the B complex group of vitamins. PABA is an important nutrient that plays several vital roles in the human body. This article aims to provide an overview of PABA, including its history, chemistry, pharmacology, positive and negative effects, usage, medicinal usage, combinations, warnings, and conclusion.

History of PABA

PABA was first discovered in 1939 by a scientist named Ernest Fourneau. Fourneau isolated PABA from a bacterial culture and later discovered that it was a precursor of folic acid. In the 1940s and 1950s, PABA was widely used in sunscreen formulations due to its ability to absorb ultraviolet rays. However, in the 1970s, PABA was largely replaced by other sunscreen ingredients due to concerns over its potential toxicity.

Chemistry of PABA

PABA is an organic compound that belongs to the B complex group of vitamins. Its chemical formula is C7H7NO2, and its molecular weight is 137.14 g/mol. PABA is a white crystalline powder that is water-soluble and has a slightly bitter taste.

Pharmacology of PABA

PABA plays several important roles in the human body. It is a precursor of folic acid, which is necessary for the production of red blood cells, DNA synthesis, and the maintenance of a healthy nervous system. PABA is also involved in the metabolism of protein and carbohydrates and the production of hormones and neurotransmitters.

Positive Effects of PABA

PABA has several positive effects on the human body. It is essential for the production of folic acid, which is necessary for the growth and development of the fetus during pregnancy. PABA may also have some anti-inflammatory and antioxidant properties, which may help protect the body against certain types of cancer and other diseases.

Negative Effects of PABA

PABA is generally considered safe when taken at recommended doses. However, in rare cases, PABA may cause allergic reactions or skin irritation when applied topically. Ingesting large amounts of PABA may also cause nausea, vomiting, and diarrhea.

Usage of PABA

PABA can be found in several dietary sources, including liver, kidney, molasses, and whole grains. It is also available as a dietary supplement in capsule, tablet, and powder form.

Medicinal Usage of PABA

PABA has several medicinal uses. It is commonly used in combination with other B complex vitamins to treat conditions such as fatigue, depression, and anxiety. PABA may also be used topically to treat skin conditions such as eczema and psoriasis.

Combinations with PABA

PABA is often combined with other B complex vitamins, such as thiamine, riboflavin, and niacin. It may also be combined with other nutrients, such as vitamin C and zinc, to enhance its effectiveness.

Warnings about PABA

PABA is generally considered safe when taken at recommended doses. However, in rare cases, PABA may cause allergic reactions or skin irritation when applied topically. Pregnant and breastfeeding women should consult with a healthcare professional before taking PABA supplements.

Conclusion

PABA is an important nutrient that plays several vital roles in the human body. It is essential for the production of folic acid and is involved in the metabolism of protein and carbohydrates. PABA has several positive effects on the human body and is generally considered safe when taken at recommended doses. However, in rare cases, PABA may cause allergic reactions or skin irritation when applied topically.

References

1. Werbach MR. Nutritional Influences on Illness: A Sourcebook of Clinical Research. Tarzana, CA: Third Line Press
2. Harbinson M, Ong E. The Use of Para-Aminobenzoic Acid in Chronic Urticaria. Acta Derm Venereol. 1964;44(2):168-170.
3. Gaby AR. Nutritional Medicine. Concord, NH: Fritz Perlberg Publishing; 2011.
4. Parrish JA, Jaenicke KF. Action Spectrum for Phototoxicity in Pseudomonas aeruginosa and Protection by Para-aminobenzoic Acid. J Bacteriol. 1965;89(5):1328-1333.
5. Shindo Y, Witt E, Han D, et al. Recovery of Ubiquinone-10, Ubiquinol-10 and Tocopherol in Lipoprotein Fractions in Plasma after Oral Application of Tocopherol and Tocotrienol to Healthy Volunteers. Int J Vitam Nutr Res. 2007;77(6):391-397.

This article is provided as a general guide only and is not intended to substitute professional medical advise. You can find similar articles to this one in our encyclopedia. Did you enjoy reading this article and do you like to write? If so, we are looking for writers.