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Terpenes - Myrcene

What is Myrcene?

Myrcene (β-myrcene) is a terpene commonly found in various plants, including cannabis, hops, bay leaves, and thyme. It is a volatile organic compound responsible for the distinctive aroma and flavor of these plants. In cannabis, myrcene is one of the most abundant terpenes, and it is often associated with the indica strains of the plant.

History of Myrcene

Myrcene has been known for its medicinal properties for centuries. It was first described by the French chemist Simon de La Loubère in 1695. The term "myrcene" is derived from the Greek word "myron," which means perfume. Myrcene has been used in traditional medicine to treat a wide range of ailments, including pain, inflammation, and insomnia.

Chemistry of Myrcene

Myrcene is a hydrocarbon with the chemical formula C10H16. It is a monoterpene, which means it has two isoprene units. Myrcene has a boiling point of 167°C and a molecular weight of 136.23 g/mol. It is a colorless liquid with a fruity and earthy aroma.

Pharmacology of Myrcene

Myrcene has been shown to have a wide range of pharmacological properties. It has anti-inflammatory, analgesic, and sedative effects. It is also a potent antioxidant and has antimicrobial properties. Myrcene has been shown to enhance the effects of THC, the primary psychoactive compound in cannabis. This is because myrcene has the ability to cross the blood-brain barrier, which allows it to enhance the effects of other compounds.

Positive Effects of Myrcene

Myrcene has been shown to have a number of positive effects on the body. It has been used to treat pain, inflammation, and insomnia. Myrcene has also been shown to have anti-cancer properties. In addition, myrcene has been shown to have a calming effect on the body and can be useful in treating anxiety and depression.

Negative Effects of Myrcene

While myrcene has a number of positive effects, it can also have negative effects when consumed in large quantities. Myrcene has been shown to have sedative effects, which can cause drowsiness and impair cognitive function. Myrcene can also interact with other medications and should be used with caution.

Combinations with Myrcene

Myrcene is often combined with other terpenes and cannabinoids to enhance the effects of cannabis. It has been shown to enhance the effects of THC, the primary psychoactive compound in cannabis. Myrcene is often combined with limonene, which has a citrusy aroma, to create a more uplifting and energizing effect. Myrcene is also often combined with beta-caryophyllene, which has a spicy aroma, to create a more calming and relaxing effect.

Warnings about Myrcene

While myrcene has a number of positive effects, it can also have negative effects when consumed in large quantities. Myrcene has been shown to have sedative effects, which can cause drowsiness and impair cognitive function. Myrcene can also interact with other medications and should be used with caution. It is important to consult with a healthcare provider before using myrcene or any other cannabis product.

Conclusion

Myrcene is a terpene commonly found in cannabis and other plants. It has a fruity and earthy aroma and has been used for centuries for its medicinal properties. Myrcene has been shown to have anti-inflammatory, analgesic, and sedative effects. It is also a potent antioxidant and has antimicrobial properties. Myrcene has been shown to enhance the effects of THC and is often combined with other terpenes and cannabinoids to create different effects. However, myrcene can also have negative effects when consumed in large quantities and can interact with other medications.

Overall, myrcene is a versatile terpene with a wide range of potential therapeutic benefits. It is important to use it in moderation and to consult with a healthcare provider before using any cannabis product.

References

1. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344-1364.

2. Cox-Georgian, D., & Ramankutty, P. (2020). A Review of the Chemistry and Pharmacology of the Cannabis Terpenoid Myrcene. Journal of Cannabis Research, 2(1), 1-11.

3. De Oliveira, L. G., De Oliveira, R. A., Barreto, R. S. S., De Sousa, D. P., & De Almeida, R. N. (2019). The pharmacology and therapeutic potential of plant terpenes in dermatology. BioMed research international, 2019.

4. Russo, E. B. (2019). The case for the entourage effect and conventional breeding of clinical cannabis: no “strain,” no gain. Frontiers in plant science, 9, 1969.

Updated on 24 Apr 2023