Study Shows DMT Protects Brain and Immune Cells Under Stress

Posted on November 07 2018

Study Shows DMT Protects Brain and Immune Cells Under Stress

DMT (N,N-dimethyltryptamine) is a potent endogenous psychedelic present in the brain of humans and other mammals. Since its discovery by the Hungarian psychiatrist Stephen Szára in 1956 its physiological role still remains largely unknown. A recent study performed by a Hungarian team led by Ede Frecska and Jordi Riba is the first to show that the DMT protects brain and immune cells under stress.

The research team team took three types of human cells - neurons derived from pluripotent stem cells, monocyte-derived macrophages and dendritic cells. They  then restricted the cells’ supply of oxygen (hypoxia) . A few hours of severe hypoxia reliably kills the majority of neurons, and a significant proportion of the immune cells.

The scientists then tested whether DMT could protect the cells from this fate. And indeed, they found that DMT-treated cell cultures had a much higher survival rate! Not only that, but the amount of DMT needed to protect the cells was relatively low (10-50μM for neurons and 50 μM for the dendrites and macrophages).

The authors of the study conclude: “Our results suggest a novel and important role of DMT in human cellular physiology and point out to the relevance of DMT-mediated Sig-1R modulation in future therapies concerning hypoxia/ischemia-related pathologies.”

If these results are applicable to other stressors and replicated in humans, the implications are huge. DMT could be administered to save neurones that would otherwise die from exposure to harmful events, such as heart attack or stroke as well as damage caused by neurodegenerative diseases, like Parkinson’s and Alzheimer’s. DMT could be a life-saving agent, administered in order to give cells, and the bodies they belong to, a second chance at life.

Source: Beckley Foundation
Original Article
: Frontiers in Neuro Science

5 comments

  • Team MindFuel: May 13, 2021

    Re: Robert – Sorry to hear. We can certainly ship Blue Lotus to you in Australia. We do not currently have an Aussie distributor so can not advise you of anyone locally I am sorry. This is a very popular product and feedback has been great, but no one has given us feedback re: using it for Parkinson’s so can not really offer any advise in this area unfortunately. All the best.

  • Robert Webby : May 13, 2021

    Hi
    I have been diagnosed for Parkinson’s recently, have the telltale signs, I think or feel it could be a combination of things I still work, but increasingly retreat from social events have tried medical marijuana in New Zealand, and Australia, but get reluctant results from pharmaceutical meds for lack of dopamine, so am abit excited to read about blue lotus, and while researching found your site, um really looking to see if your customers have tried your stuff and what results, I will buy some and while I am stuck in Australia do you recommend a supplier here till I can get back to NZ
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  • Team MindFuel: November 09, 2020

    Re: Dion – No, we do not stock that species, it is not permitted to be imported by MPI. A guy was charged for importing a few years back…

    Re: Rhys – DMT is a class A drug here in New Zealand. Its everywhere in nature but not common as a street drug on the black market here in NZ. It is being studied as a medicine overseas and available in various brews utilized by Sth American Shaman. In the longer term hopefully it will be available here as a prescription medicine.

  • rhys: November 09, 2020

    Can you buy dmt anywhere in New zealand ?

  • Dion: April 25, 2019

    Do you guys stock Mimosa hostilis? I could not see it on your website.

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